Long-term results of GH therapy in GH-deficient children treated before 1 year of age
نویسندگان
چکیده
منابع مشابه
Long-term results of GH therapy in GH-deficient children treated before 1 year of age.
OBJECTIVES To evaluate the long-term effects of GH therapy in early diagnosed GH-deficient patients treated before 1 year of age. STUDY DESIGN We studied all 59 patients (33 males) recorded by Association France-Hypophyse and treated with GH (0.50+/-0.15 IU/kg (S.D.) per week) before 1 year of age. Clinical presentation and growth parameters under GH treatment were analyzed. RESULTS Neonata...
متن کاملBirth weight influences long-term catch-up growth and height prognosis of GH-deficient children treated before the age of 2 years.
OBJECTIVE To investigate which pretreatment variables most significantly affect long-term growth response to GH therapy in children with apparently idiopathic GH deficiency (GHD) treated from a similar and very young age (less than 2 years), for the same period (7 years) and with the same therapeutic protocol. DESIGN AND METHODS Twelve children with either isolated GHD or multiple pituitary h...
متن کاملThree-Year Follow-up Study on Serum Leptin Levels in GH Deficient Children with GH Replacement Therapy
Interactions between GH and leptin have been extensively studied. However, results of long-term GH therapy on serum leptin levels in GH-deficient children were not consistent. Moreover, no such reports were available in Japanese children with this disease. We studied 35 Japanese patients with GH deficiency (26 boys and 9 girls, mean age: 9.8 ± 6.2 yr old), of whom 6 patients with complete and 2...
متن کاملDoes long-term GH replacement therapy in hypopituitary adults with GH deficiency normalise quality of life?
OBJECTIVE To determine whether impaired quality of life (QoL) in adults with GH deficiency (GHD) is reversible with long-term GH therapy and whether the responses in QoL dimensions differ from each other. METHODS QoL was measured by the Quality of Life-Assessment for Growth Hormone Deficiency in Adults (QoL-AGHDA) in general population samples in England & Wales, The Netherlands, Spain and Sw...
متن کاملProspective Safety Surveillance of GH-Deficient Adults: Comparison of GH-Treated vs Untreated Patients
CONTEXT In clinical practice, the safety profile of GH replacement therapy for GH-deficient adults compared with no replacement therapy is unknown. OBJECTIVE The objective of this study was to compare adverse events (AEs) in GH-deficient adults who were GH-treated with those in GH-deficient adults who did not receive GH replacement. DESIGN AND SETTING This was a prospective observational st...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 1999
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1400029